Wound Healing Potential of Formulated Extract from Hibiscus Sabdariffa Calyx

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Wound Healing Potential of Formulated Extract from Hibiscus Sabdariffa Calyx

Wound healing agents support the natural healing process, reduce trauma and likelihood of secondary infections and hasten wound closure. The wound healing activities of water in oil cream of the methanol extract of Hibiscus sabdariffa L. (Malvaceae) was evaluated in rats with superficial skin excision wounds. Antibacterial activities against Pseudomonas aeroginosa, Staphylococcus aureus and Ech...

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Toxic Effects of Hibiscus Sabdariffa Calyx

The effects of a 90-day oral administration of water and alcohol extracts of dried calyx of Hibiscus sabdariffa were evaluated in albino rats. Haematological, biochemical and histopathological changes were monitored every 30 days. The death of the animals was preceded by a severe loss in weight, accompanied with diarrhoea in animals on the 2000 mg/kg dose. There was an increase in food intake (...

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Hibiscus sabdariffa L., roselle calyx, from ethnobotany to pharmacology.

Using MEDLINE and SCOPUS databases, a review of the literature from the pioneering study of 1991 until 2010 was performed on the effects on biological models of Hibiscus sabdariffa L. roselle calyx, its extracts mainly in polar solvents, or pure components found in extracts, as well as their possible relationship to these effects. Three relevant effects on lipid metabolism, antihypertensive act...

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Attenuation of salt-induced hypertension by aqueous calyx extract of Hibiscus sabdariffa.

The aqueous calyx extract of Hibiscus sabdariffa (HS) has a folk reputation as an antihypertensive agent. On account of its antioxidant properties and probably high K+ concentration, we hypothesized that HS may attenuate the development of salt-induced hypertension. Sprague-Dawley rats (n=8 each) were treated for 12 weeks as follows: control (normal diet + water), salt-loaded (8% salt diet + wa...

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Effect of Hibiscus sabdariffa calyx extract on carbon tetrachloride induced liver damage

The effect of aqueous ethanol (1:1) extract of the calyx of Hibiscus sabdariffa on carbon tetrachloride (CCl4) induced liver damage was investigated. Oral administration of the extract following a single CCl4 dose promoted the healing of oxidative liver damage as determined by serum aminotransferases, ALT, AST, levels and liver thiobarbituric acid reactive substances levels. It appeared from th...

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ژورنال

عنوان ژورنال: Indian Journal of Pharmaceutical Sciences

سال: 2013

ISSN: 0250-474X

DOI: 10.4103/0250-474x.113549